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When searching for articles, you can search by subject or by keyword. When you search a database by keyword, the system looks for the term you've entered as you've entered it. Spelling and context are important. If you misspell a word, you may not find any results. If you use a word in a different context, you may get results that are not useful. If you use a variant of a word different from what most authors use, you may not get the most important articles. The more terms you include, the more likely you are to get results that are useful.
The PubMed default is searching by keyword. Enter the term(s), you're looking for and click on the Search button.