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SEARCHING FOR A THERAPY QUESTION




For a quick answer to any evidence-based question, the format for a PubMed search is the same:

1) Search for the disease/condition

2) Search for the intervention (drug, surgery, diagnostic test, screening test, prognostic indicator)

3) Add the appropriate "filter" for that particular type of question.  




The proper filter for a therapy question is to search for the desired level of evidence.  For a therapy question, the highest level of evidence would be a meta-analysis, followed by a systematic review, and then a single prospective randomized blinded placebo-controlled clinical trial.  

For example, if you wanted to search for information on whether it would be appropriate to use the antibiotic amoxicillin for a six-month old with otitis media, you would take the following steps.


1)  Click on the link at the bottom of the screen to enter the MeSH database.

2)   Enter the term "otitis media" in the search box. Click in the box next to the term "Otitis Media."  Click on the button labeled "Add to Search Builder" on the right side of the screen.

3) Enter the term "amoxicillin" in the search box.  Click in the box next to the term "Amoxicillin". Click on the button labeled "Add to Search Builder" on the right side of the screen.



4) Enter the term "randomized clinical trial" in the search box. Click in the boxes next to "Randomized Controlled Trial as Topic" and "Randomized Controlled Trial [Publication Type]". Click on the button labeled "Add to Search Builder" on the right side of the screen.



5) Click on the button labeled "Search PubMed".  



Access PubMed


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